Organic Chemisry II (Wade)

CHEM 302 - Spring 2009 Organic Chemistry II (4 cr.)

MWF: 9:00 - 9:50 pm

Instructor: Dr. Sapna Gupta
Email: This email address is being protected from spambots. You need JavaScript enabled to view it.
Telephone: 540-665-4591

Office: Gregory 214
Office hours: 1:30-2:30 pm MWF and 11:30-1:30 pm R or by appointment

Text
Organic Chemistry, 6th Edition by L. G. Wade, ISBN: 013-187151
Highly Recommended: Organic Chemistry as a Second Language, Dr. David R. Klein, (ISBN: 978-0-470-12929-6)

Course Description
A comprehensive introduction to the modern theories of organic structure and reactivity. Three hour lecture plus three-hour laboratory per week.

Course Objectives
On completion of this course the student should be able to:
• Apply spectroscopic analysis (NMR, UV-Vis, IR, GC-MS etc) to organic compounds.
• Name conjugated systems, phenols and the following homologous series: aromatic, aldehydes and ketones, carboxylic acids and its derivatives, amines.
• Explain and predict the synthesis, properties, reactions and applications of the above-mentioned classes of compounds.
• Integrate and apply topics in CHEM301 and CHEM302: nomenclature, synthesis and reactions, synthesis and reactions, to biological compounds, e.g. carbohydrates, proteins, and lipids.
• Carry out multistep synthesis of molecules.

Course Policies (top )

Prerequisite
CHEM 122 and CHEM301 or permission of the instructor.

Text
1. Required: Organic Chemistry, 8th Edition by T. W. Graham Solomons, Craig B. Fryhle
(ISBN: 978-0-471-41799-6)
2. Recommended: Organic Chemistry as a Second Language, Dr. David R. Klein
(ISBN: 978-0-470-12929-6)

Attendance Policy
1. It is the policy of the College of Arts and Science, that if a student misses more than 20 percent of the contact hours in a course, for any reason, the student will have to withdraw from the course before the withdrawal deadline or receive an “F” as a final grade. The instructor may modify this policy according to the nature of the course.
2. It is highly advisable that you withdraw from the course if you miss more than 3 lectures consecutively. You will get an “F” in the course if you miss 6 lectures consecutively.
3. There are no makeup quizzes or homework assignments. Exams can only be made up with instructor’s permission and a valid reason.

Plagiarism and Honor Code
Plagiarism—the appropriation or imitation of the language or ideas of another person and presenting them as one’s original work—sometimes occurs through carelessness or ignorance. Students who are uncertain about proper documentation of sources should consult their instructors.” All issues addressed in the Student Handbook regarding Honor Code will be enforced. You are urged to read that section. The Student handbook is available online.

Disability Policy
If you need course adaptation or accommodations because of a disability, if you have emergency medical information to share with me, or if you need special arrangements in case the building needs to be evacuated, please contact me and Debby Wyne in the Academic Support Center (Howe, 105), as soon as possible.

Late Submission Of Course Materials
1. Class quizzes and exams cannot be made up.
2. Homework is to be submitted on the dates given during class and at the beginning of the class. 20% of the score will be deducted for each day the assignment is submitted late.
3. Homework submitted after the assignment has been returned or submitted after one class time will not be accepted for grading.

Course Assessment (top )

Quizzes	6%	There will be a number of pop quizzes during the semester. Most quizzes will be 5-10 mins long. There may also be some electronic quizzes on the web.
Homework	7%	Homework will be assigned in class after a chapter is ended. The problems will mostly be from the end of the chapter problems. The dates of submission of homework will be announced in the class.
Mid-Term Exams	39%	4 mid term exams: (13% each) on 4 Feb., 27 Feb, 27 March, 17 April (all Fridays); each exam will be one hour long, not comprehensive. The lowest score of the four exams will be dropped.
Final Exam	20%	1 final exam. 2 hours long and comprehensive.
Class participation	3%	Read the information on “Being an Ideal Student” on Blackboard website.
Lab Grade	25%	Explained in the lab syllabus

Please note: You will be informed ahead of time any changes made in the above schedules.
Unexcused absence of 6 lectures will result in a F in the class.

Grading scale

(This is an approximate scale. I reserve the right to make adjustments based on perceived effort, significant improvement, and other factors.)

A	90 and above
B	80-89
C	70-79
D	60-69
F	59 and below

Topics To Be Covered (top )

Chapter	Topics	Practice
Chapter 10	Structure and Synthesis of Alcohols: continue with Organometallic reagents
Chapter 11	Reactions of Alcohols: oxidation etc.
Chapter 14	Ethers and Epoxides: nomenclature, synthesis and reactions
Chapter 15	Conjugated systems: Polyenes, Resonance, Diels Alder Reaction
Chapter12, Chapter 13 and Chapter 15 - topic 13	Structure determination using spectroscopic techniques: Infra-red spectroscopy, Ultraviolet spectroscopy, Mass Spectroscopy, Nuclear magnetic resonance, Gas chromatography.
Chapter 16	Aromatic Compounds: Introduction to aromaticity; Rules for aromaticity, Heteroaromatic compounds, Spectroscopy of aromatic compounds
Chapter 17	Reactions of Aromatic Compounds: Revision of electrophilic substitution; Substitution on benzene ring; Substituent effect on disubstitution.
Chapter 18	Aldehydes and Ketones: Nomenclature, properties, synthesis and reactions.
Chapters 22	Aldol Reactions - Topics 22:1 - 22:11
Chapter 20	Carboxylic Acids: Nomenclature, properties, synthesis and reactions.
Chapters 19	Amines: Nomenclature, properties, synthesis and reactions.
Chapters 23, 24 and 25	Biomolecules: Introduction to: Carbohydrates, Lipids Proteins and Nucleic acids.

Good Links

Nomenclature

Basic: http://www.cem.msu.edu/~reusch/VirtualText/nomen1.htm
More functional groups: http://www.chem.ucalgary.ca/courses/351/orgnom/index.html

Quizzes

	http://www.mhhe.com/physsci/chemistry/carey/student/olc/index.htm. Try this text book notes. There are also quizzes at the end of chapter. See how you perform on them.
	From Carey Book Site: http://highered.mcgraw-hill.com/sites/0072424583/student_view0/chapter_tutorials.html
	Organic Chemistry Practice at MSU: http://www.cem.msu.edu/~reusch/VirtualText/Questions/problems.htm

Tests

http://www.chem.wisc.edu/~concept/ . You can print these out and we can do them in the class practice time.

Good Notes

www.chemhelper.com

Spectroscopy

Nuclear Magnetic Resonance: (http://www.cis.rit.edu/htbooks/nmr/inside.htm)

Practice Problems and Databases

Molecules:

Molecular Library: http://www.nyu.edu/pages/mathmol/library/index.html
Molecular Structure Calculations: http://www.colby.edu/chemistry/webmo/mointro.html
Interesting Molecules: http://www.reciprocalnet.org/common/index.html
3D Virtual Chemistry: http://www.ch.ic.ac.uk/vchemlib/mol/mol.html
Chemistry Connections: http://mc2.cchem.berkeley.edu/Smells/index.html
Hemoglobin: http://www.umass.edu/microbio/chime/hemoglob/index.htm
Dendrimers: http://www.wag.caltech.edu/gallery/gallery_dendrimer.html#dendbox